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iTransition: Developing and Testing a Web App to Support Youth Living with HIV and the Transition from Pediatric to Adult Care

Statement of Problem

Of the approximately 38,000 new HIV diagnoses in the U.S. in 2018, 21% of those cases were among youth ages 13-24 years. Youth living with HIV will all experience a health care transition from pediatric/adolescent HIV care to adult care, and this care transition can be disruptive to care engagement. Yet, this period is crucial for youth living with HIV to continue working on and maintaining their health goals and achievements (e.g., undetectable viral load).

Unfortunately, youth living with HIV face several barriers to health care transition on the individual, clinical and structural levels. For example, insufficient preparation for disease self-management over 18 (individual), lack of quality inter-clinic communication to facilitate health care transition (clinical), and financial and transportation difficulties (structural) all contribute to poor health care transition outcomes.

Despite these challenges, there are no existing evidence-based interventions that are tailored by and for youth living with HIV to improve the health care transition process. However, mobile health (mHealth) and electronic Health (eHealth) interventions have been shown to be useful tools for improving medication adherence as well as care engagement for youth living with various chronic illnesses, and may be useful to youth living with HIV in the health care transition process to keep young adults engaged and retained in care during their care transition.

Description

iTransition: Developing and Testing a Web App to Support Youth Living with HIV and the Transition from Pediatric to Adult Care

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We seek to inform the development of culturally sensitive and appropriate digital interventions to improve health care transition for youth living with HIV.

Next Steps

The iTransition study provided key preliminary data for future development of mHealth interventions that are culturally sensitive and appropriate for health care transition engagement and retention, as well as have broad implications for improving the pediatric/adolescent to adult health care transition experience and clinical outcomes for youth and providers.

Published abstracts:

  1. Tanner AE, Dowshen N, Lee S, Goldstein M, Doraivelu K, Knowles K, et al. Development and usability testing of iTransition: an mHealth intervention to support patients' movement from pediatric- to adult-oriented HIV care. 24th Annual International AIDS Conference (AIDS 2022), Montreal, QC, Canada, July-August 2022.

  2. Tanner AE, Dowshen N, Rulison KR, Pather A, Knowles K, Goldstein M, et al. 198. Developing and Pilot Testing iTransition: A multilevel mHealth Intervention to Support Transition to Adult Care for Youth Living with HIV - Journal of Adolescent Health. Society for Adolescent Health and Medicine Annual Meeting, Chicago, IL/Virtual, March 2023.

  3. Hussen SA, Dowshen N, Rulison KR, Doraivelu K, Knowles K, Goldstein M, et al. 1127. Lessons Learned from iTransition: An mHealth Intervention to Support Transition to Adult Care for Youth Living with HIV. 18th International Conference on HIV Treatment and Prevention Adherence, International Association of Providers of AIDS Care (IAPAC), Fajardo, PR, June 2023.

  4. Urquhart R, Phillips K, Jibriel MSE, Mertus S, Dutta S, Lee S, et al. 178. Transiting Adolescents to Adult Hiv Care: Implementation Lessons From the Itransition Pilot Study - Journal of Adolescent Health. Society for Adolescent Health and Medicine Annual Meeting, Baltimore, MD, March 2025.

Published articles: 

  1. Tanner AE, Dowshen N, Philbin MM, Rulison KL, Camacho-Gonzalez A, Lee S, et al. An Intervention for the Transition From Pediatric or Adolescent to Adult-Oriented HIV Care: Protocol for the Development and Pilot Implementation of iTransition. JMIR Res Protoc. 2021;10(4):e24565.

  2. Tanner AE, Mertus S, Jibriel MSE, Urquhart R, Phillips K, Dowshen N, et al. Transitioning Adolescents to Adult HIV Care in the United States: Implementation Lessons from the iTransition Intervention Pilot Trial. Trop Med Infect Dis. 2024;9(12).

  3. Tanner AE, Jibriel MSE, Rulison, KL, Mertus S, Urquhart R, Phillips K, et al. Supporting youth from pediatric- to adult-oriented HIV care across two metro sites in the United States: Results from the iTransition pilot trial. AIDS Patient Care STDS. 2026;0(0).

This project page was updated in February 2026.

Suggested Citation

Children's Hospital of Philadelphia, PolicyLab. iTransition: Developing and Testing a Web App to Support Youth Living with HIV and the Transition from Pediatric to Adult Care [Online]. Available at: http://www.policylab.chop.edu. [Accessed: plug in date accessed here]. 

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